Andersen EOGas 4PLUS Ethylene Oxide Sterilizer (FDA-Approved). 
Product code: NANEOG4Plus
FDA-cleared for complex endoscopes & longest lumens
The EOGas 4PLUS sets a new standard for reprocessing difficult-to-sterilize medical devices, including duodenoscopes and colonoscopes. Powered by EO-Flexible Chamber Technology (EO-FCT), it achieves terminal sterilization using a 17.6g EO microdose—up to 90% less EO than traditional systems. The system supports active aeration in the same chamber, controlled temperature circulation, automated door locking, and a user-friendly touchscreen interface. When paired with an optional ETO Cartridge Abator, it delivers zero-emissions performance, expanding sterilization capability for heat- and moisture-sensitive instruments.
EOGas 4PLUS Advantage
Comparison Chart
Additional Clearances:
Product code: NANEOG4Plus
FDA-cleared for complex endoscopes & longest lumens
The EOGas 4PLUS sets a new standard for reprocessing difficult-to-sterilize medical devices, including duodenoscopes and colonoscopes. Powered by EO-Flexible Chamber Technology (EO-FCT), it achieves terminal sterilization using a 17.6g EO microdose—up to 90% less EO than traditional systems. The system supports active aeration in the same chamber, controlled temperature circulation, automated door locking, and a user-friendly touchscreen interface. When paired with an optional ETO Cartridge Abator, it delivers zero-emissions performance, expanding sterilization capability for heat- and moisture-sensitive instruments.
Key Features:
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FDA-cleared for terminal sterilization of complex long-lumen devices
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EO-FCT technology using 17.6g microdose EO per cycle
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Zero emissions when paired with Andersen abator
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Efficient 3.5-hour cycle achieving 10⁻⁶ sterility assurance level
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Active aeration in the same chamber (no device transfer required)
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Touchscreen interface with real-time cycle guidance
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Automatic door locking during sterilization cycles
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Process Challenge Device built into purge probe for consistent BI placement
EOGas 4PLUS Advantage
- Compared to Steam: Steam can damage heat-sensitive materials → EOGas 4PLUS preserves delicate devices
- Compared to Hydrogen Peroxide (H₂O₂): H₂O₂ may degrade polymers and complex lumens → EOGas 4PLUS supports long-lumen compatibility
- Compared to Traditional EO: Uses significantly less EO Lower emissions, smaller footprint, modern workflow
Comparison Chart
| Category | EOGas 4 | EOGas 4PLUS |
|---|---|---|
| Positioning | Proven EO sterilizer for long lumens and heat-sensitive devices | Next-generation EO platform for complex endoscopes and high-risk devices |
| Primary Use Case | General long-lumen and delicate device sterilization | Advanced terminal sterilization for duodenoscopes, colonoscopes, and complex lumens |
| FDA Clearance | Terminal sterilization of long-lumen devices | FDA-cleared for terminal sterilization of duodenoscopes & colonoscopes |
| Chamber Technology | Traditional chamber | EO-Flexible Chamber Technology (EO-FCT) |
| EO Dose per Cycle | Low-dose EO | Microdose EO (17.6 g) |
| EO Efficiency | Reduced EO usage | Up to 90% less EO than rigid-chamber EO systems |
| Lumen Compatibility | Long-lumen capable | Validated for >1100 mm working lumens |
| Sterility Assurance Level | SAL 10⁻⁶ | SAL 10⁻⁶ (FDA-required) |
| Cycle & Workflow | Standard EO cycle | ~3.5-hour efficient cycle with integrated aeration |
| Sterilization + Aeration | Aeration supported | Sterilization and aeration in the same chamber |
| Endoscope Optimization | Not endoscope-specific | Designed for flexible endoscopes, duodenoscopes, and colonoscopes |
| Environmental Impact | Low EO emissions | Near-zero emissions with Andersen abator |
| Process Monitoring | Standard monitoring | Process Challenge Device integrated into purge probe |
| User Interface | Standard controls | Touchscreen with real-time cycle guidance |
| Safety Features | Standard door safety | Automatic door locking during cycle |
| Temperature Control | Controlled chamber environment | Warm-air circulation for stable sterilization & aeration |
| Facility Fit | ASCs, veterinary, SPD, outpatient | Hospitals, endoscopy centers, advanced SPD departments |
| Cost Positioning | Cost-effective EO solution | Premium, compliance-forward flagship system |
| Key Advantage | Proven reliability, lower acquisition cost | Higher regulatory confidence, lower EO usage, expanded device compatibility |
Additional Clearances:
The EOGas 4PLUS is also cleared for sterilization of metal, plastic, and fabric loads.
Sterility Assurance Level: SAL 10⁻⁶ (FDA-required for terminal sterilization)
WARRANTY: 12 months parts only
Technical Specs
- Chamber Size: 25.25” L × 18” W × 14” H
- Exterior Dimensions: 29.5” L × 22” W × 28” H
- Weight: 161 lb (73 kg
- Electrical: 115V (installation supports 120V or 240V outlet
- EO Dose: 17.6 grams per cycle
| Exposure | Device Specifications | Maximum Load - Duodenoscopes | Maximum Load - Colonoscopes |
|---|---|---|---|
|
6-Hour Cycle |
>1100 mm working lumen length endoscopes
• Working lumen length: ≤1250 mm (duodenoscopes) / ≤1700 mm (colonoscopes)
• Channel ID: ≥1.2 mm
• Maximum channel length: ≤3530 mm
|
Two (2) duodenoscopes*
• Biopsy channel: ≥2.0 mm ID
• Working length: ≤1250 mm
• Maximum channel length: ≤3530 mm
*or one duodenoscope may be paired with one colonoscope
|
Two (2) colonoscopes*
• Biopsy channel: ≥3.7 mm ID
• Working length: ≤1700 mm
• Maximum channel length: ≤3530 mm
*or one colonoscope may be paired with one duodenoscope
|
|
3-Hour Cycle |
≤1100 mm working lumen length endoscopes
• Working lumen length: ≤1100 mm (biopsy channel endoscopes) / ≤700 mm (lumen endoscopes)
• Channel ID: ≥1.2 mm
|
One (1) endoscope
• Biopsy channel: ≥2.0 mm ID
• Working length: ≤1100 mm
|
Four (4) endoscopes
• Biopsy channel: ≥1.2 mm ID
• Working length: ≤700
|
EOGas 4Plus Sterilizer Brochure
EO Gas 4 FDA Clearance
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EO Gas 4 FDA Clearance
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Andersen’s FDA 510(K) Clearances –fda.gov
A 510(k) is a premarket submission made to FDA to demonstrate that the device to be marketed is as safe and effective, that is, substantially equivalent, to a legally marketed device.
Q. What is EOGas 4Plus
A. EOGas 4Plus is an advanced gas sterilization system designed for efficiency and reliability. It utilizes a microdose of ethylene oxide to ensure sterilization of medical instruments. This system is ideal for facilities seeking a reliable solution to sterilization needs.
Q. How does EOGas 4Plus work?
A. The EOGas 4 PLUS operates by introducing ethylene oxide gas into a impermeable flexible chamber containing the devices to be sterilized. The gas penetrates packaging and surfaces, effectively killing bacteria and viruses. After a designated exposure time, the gas is evacuated, leaving devices terminally sterile with a shelf life of up to six months.
Q. Is it safe to use?
A. The chamber wash pump flow rate is100 L/mn
Q. What devices is EOGas 4PLUS intended for?
A. Heat- and moisture-sensitive devices, including duodenoscopes, colonoscopes, and long-lumen instruments.
Q. Does it require a separate aeration cabinet?
A. No. Sterilization and active aeration occur in the same chamber.
A. EOGas 4Plus is an advanced gas sterilization system designed for efficiency and reliability. It utilizes a microdose of ethylene oxide to ensure sterilization of medical instruments. This system is ideal for facilities seeking a reliable solution to sterilization needs.
Q. How does EOGas 4Plus work?
A. The EOGas 4 PLUS operates by introducing ethylene oxide gas into a impermeable flexible chamber containing the devices to be sterilized. The gas penetrates packaging and surfaces, effectively killing bacteria and viruses. After a designated exposure time, the gas is evacuated, leaving devices terminally sterile with a shelf life of up to six months.
Q. Is it safe to use?
A. The chamber wash pump flow rate is100 L/mn
Q. What devices is EOGas 4PLUS intended for?
A. Heat- and moisture-sensitive devices, including duodenoscopes, colonoscopes, and long-lumen instruments.
Q. Does it require a separate aeration cabinet?
A. No. Sterilization and active aeration occur in the same chamber.
Sterility Assurance Level: SAL 10⁻⁶ (FDA-required for terminal sterilization) WARRANTY: 12 months parts only